In euphoria is rue gay

Rue has had a complicated relationship with her sexuality, struggling with compulsory heterosexuality. She experienced uncomfortable sexual situations with boys when she was younger (such as being "emotionally coerced" in to a blowjob) before realizing that she is a lesbian.

Jules and Elliott have a conversation about Rue’s sexuality, with Elliott hinting that Rue is asexual. In the past, Rue has shown little inclination towards sexual activities and keeps her sexual desires hidden.